Negligible influence of moderate to severe hyperthermia on blood-brain barrier permeability and neuronal parenchymal integrity in healthy men

نویسندگان

چکیده

The acute effects of passive whole-body hyperthermia on the integrity neurovascular unit (NVU) in humans have remained unclear. We demonstrate that heating for ∼1 h until an increase +2°C esophageal temperature healthy men does not cerebral release neuronal parenchymal stress biomarkers, suggesting NVU is maintained. This preliminary study indicates safe brain, at least young men.

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ژورنال

عنوان ژورنال: Journal of Applied Physiology

سال: 2021

ISSN: ['1522-1601', '8750-7587']

DOI: https://doi.org/10.1152/japplphysiol.00645.2020